> > 海外>

英国Babraham研究所招聘淋巴细胞生物学博士后

2011-06-15 16:48 来源: 未知 作者: admin

Employer: Babraham Institute
Website:http://www.babraham.ac.uk
Location: Cambridge, United Kingdom
Type: Postdoctoral
Posted: June 13, 2011
Expires: July 14, 2011
Jobs by tag(s): babraham institute postdoctoral research scientist Cambridge united kingdom biological sciences cell biology development pathology babraham research scientist postdoctoral
Requisition number: LR / BHF / ST
job description

Regulation of InsP3R expression during cardiac hypertrophy
Postdoctoral Research Scientist

Starting salary in range £28,409 to £29,356 p.a.

The Babraham Institute is a charity which is world renowned for its research in life sciences to enhance lives and improve wellbeing.

We are seeking a talented Postdoctoral Research Scientist to study the regulation of expression of the inositol 1,4, 5 triphosphate receptor (InsP3R) intracellular calcium release channel by microRNA-133 during cardiac hypertrophy. This project aims to develop our previous findings that show that calcium signals arising from InsP3Rs contribute to the induction of cardiac hypertrophy (Higazi et al., 2009. Mol Cell) as well as to the pathology associated with it (Harzheim et al., 2009. PNAS), which place InsP3Rs as key regulators of myocyte function during health and disease.

The project will use cell and animal models of hypertrophy to dissect out the contribution of this miRNA pathway to regulation of InsP3R expression. Adenoviral approaches will be used to manipulate key regulators of hypertrophy-associated pathways in vitro and combinations of cell imaging, ChIP and qPCR to quantitate hypertrophic responses. Confocal imaging will be extensively used to assay calcium signalling mechanisms in primary cardiac myocytes and visualise translocation of GFP-tagged proteins.

Applicants must have a PhD in Cell Biology or Physiology. They must also have a working knowledge of signalling pathways, microRNA function and experience in calcium imaging as well as in cardiac physiology. They must also have experience in molecular biology and biochemical techniques as well as in good laboratory practice. Further information on the position may be made to Llew Roderick (llewelyn.roderick@bbsrc.ac.uk). This is a limited term contract with funding available for up to 2 years.

Further information about the Institute can be found on our website. Application forms and further details are available electronically from our website (http://www.babraham.ac.uk), or by contacting our 24-hour Recruitment Line on 01223 496365, or e-mail:babraham.personnel@bbsrc.ac.uk. On applying please quote reference LR/BHF/ST. Closing date for completed applications is 14 July 2011.

The Babraham Institute is a user of the disability symbol and is positive about disabled people

The Babraham Institute receives strategic funding from the Biotechnology and Biological Sciences Research Council and is an Equal Opportunities Employer.

    声明:凡本网注明"来源:XXX"的文/图等稿件,本网转载出于传递更多信息及方便产业探讨之目的,并不意味着本站赞同其观点或证实其内容的真实性,文章内容仅供参考。如其他媒体、网站或个人从本网站转载使用,须保留本网站注明的“来源”,并自负版权等法律责任。作者如果不希望被转载或者联系转载等事宜,请与我们联系。

    海归QQ群

    申请加群请以“留学国家-目前所在地”格士发送请求,群有人数上限,每人只能加一个群。
    海归部落千人群
    63984971
    海归部落2号群
    103237942
    上海海归人才2号群
    461068872
    北京海归人才群
    63984971
    上海海归人才群
    103237942
    天津海归人才群
    461068872
    重庆海归人才群
    172719654
    山东海归人才群
    462302845
    江苏海归人才群
    172331746
    浙江海归人才群
    314125833
    江西海归人才群
    463247306
    福建海归人才群
    457497619
    安徽海归人才群
    457823891
    河南海归人才群
    264015004
    湖北海归人才群
    109623634
    湖南海归人才群
    458690950
    广东海归人才群
    432013578
    海南海归人才群
    312160331
    黑龙江海归人才群
    312929192
    吉林海归人才群
    313316571
    辽宁海归人才群
    109899038
    河北海归人才群
    282994183
    陕西海归人才群
    315357786
    甘肃海归人才群
    315753165
    宁夏海归人才群
    517762915
    青海海归人才群
    319457961
    四川海归人才群
    517765170
    云南海归人才群
    432350311
    贵州海归人才群
    517766496
    广西海归人才群
    517767217

    Baidu
    map